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- Recognize signsBreathing problems, swelling throat/tongue/lips, sudden rash, nausea, fainting.
- Use the adrenaline auto-injector (EpiPen)Does the person have an EpiPen or other adrenaline pen? Inject into the outer thigh, through clothing is fine. EpiPen: hold for 3 seconds. Other brands: follow their own instructions leaflet.
- Call 112 immediatelyAlways call 112 for anaphylaxis — even if the person improves after the pen. Adrenaline wears off quickly.
- PositionLay down with legs raised. Difficulty breathing: sit upright. Do not let them stand up or walk. Unconscious: recovery position.
- No improvement? Second doseNo improvement after 5–15 minutes and a second pen available? Give a second dose, in the other thigh.
- Cardiac arrest → CPRStart CPR immediately if the person stops breathing.
Checked in October 2026 against the guidelines of the Red Cross, the Dutch Resuscitation Council (2025), the European Resuscitation Council, the Dutch public health institute RIVM and the NHS. This does not replace a first-aid course. If a life is in danger: call 112 straight away.
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